2. Fussball Bundesliga 2005/06 Liga
| 1 | 07.08.2005 13:00 | SpVgg Unterhaching | – | SC Paderborn 07 | 3 : 0 | |
| 2 | 14.08.2005 13:00 | SC Paderborn 07 | – | 1. FC Saarbrücken | 5 : 0 | |
| 3 | 28.08.2005 13:00 | FC Energie Cottbus | – | SC Paderborn 07 | 1 : 2 | |
| 4 | 11.09.2005 13:00 | SC Paderborn 07 | – | Rot Weiss Ahlen | 1 : 0 | |
| 5 | 18.09.2005 13:00 | FC Hansa Rostock | – | SC Paderborn 07 | 2 : 0 | |
| 6 | 21.09.2005 15:30 | SC Paderborn 07 | – | SpVgg Greuther Fürth | 1 : 2 | |
| 7 | 25.09.2005 13:00 | SG Dynamo Dresden | – | SC Paderborn 07 | 0 : 2 | |
| 8 | 02.10.2005 13:00 | SC Paderborn 07 | – | Kickers Offenbach | 4 : 1 | |
| 9 | 14.10.2005 17:00 | TSV 1860 München | – | SC Paderborn 07 | 1 : 0 | |
| 10 | 21.10.2005 17:00 | SC Paderborn 07 | – | Eintracht Braunschweig | 3 : 0 | |
| 11 | 28.10.2005 17:00 | VfL Bochum 1848 | – | SC Paderborn 07 | 1 : 1 | |
| 12 | 06.11.2005 14:00 | SC Paderborn 07 | – | SC Freiburg | 1 : 1 | |
| 13 | 18.11.2005 18:00 | SC Paderborn 07 | – | Sportfreunde Siegen | 4 : 0 | |
| 14 | 27.11.2005 14:00 | Alemannia Aachen | – | SC Paderborn 07 | 2 : 1 | |
| 15 | 04.12.2005 14:00 | SC Paderborn 07 | – | SV Wacker Burghausen | 1 : 3 | |
| 16 | 09.12.2005 17:00 | FC Erzgebirge Aue | – | SC Paderborn 07 | 1 : 0 | |
| 17 | 19.12.2005 19:15 | SC Paderborn 07 | – | Karlsruher SC | 2 : 0 | |
| 18 | 22.01.2006 14:00 | SC Paderborn 07 | – | SpVgg Unterhaching | 1 : 1 | |
| 19 | 28.01.2006 12:00 | 1. FC Saarbrücken | – | SC Paderborn 07 | 0 : 0 | |
| 20 | 05.02.2006 14:00 | SC Paderborn 07 | – | FC Energie Cottbus | 0 : 0 | |
| 21 | 12.02.2006 14:00 | Rot Weiss Ahlen | – | SC Paderborn 07 | 0 : 2 | |
| 22 | 19.02.2006 14:00 | SC Paderborn 07 | – | FC Hansa Rostock | 3 : 0 | |
| 23 | 24.02.2006 18:00 | SpVgg Greuther Fürth | – | SC Paderborn 07 | 1 : 1 | |
| 24 | 05.03.2006 14:00 | SC Paderborn 07 | – | SG Dynamo Dresden | 0 : 2 | |
| 25 | 10.03.2006 18:00 | Kickers Offenbach | – | SC Paderborn 07 | 1 : 1 | |
| 26 | 19.03.2006 14:00 | SC Paderborn 07 | – | TSV 1860 München | 0 : 1 | |
| 27 | 24.03.2006 18:00 | Eintracht Braunschweig | – | SC Paderborn 07 | 2 : 0 | |
| 28 | 31.03.2006 17:00 | SC Paderborn 07 | – | VfL Bochum 1848 | 1 : 3 | |
| 29 | 09.04.2006 13:00 | SC Freiburg | – | SC Paderborn 07 | 1 : 0 | |
| 30 | 13.04.2006 17:00 | Sportfreunde Siegen | – | SC Paderborn 07 | 0 : 2 | |
| 31 | 21.04.2006 17:00 | SC Paderborn 07 | – | Alemannia Aachen | 3 : 1 | |
| 32 | 02.05.2006 15:30 | SV Wacker Burghausen | – | SC Paderborn 07 | 5 : 1 | |
| 33 | 07.05.2006 13:00 | SC Paderborn 07 | – | FC Erzgebirge Aue | 0 : 2 | |
| 34 | 14.05.2006 13:00 | Karlsruher SC | – | SC Paderborn 07 | 2 : 3 |